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Yes, indeed!  Can't tell you which reputable, world-renowned resort is having problems with bed bug infestations because I swore my client I would not divulge the name ot it.  It turns out that she went to this resort on vacation a month or so ago and her son got bitten all over his little body.
Upon returning back home, she called the resort to find out if they had had a problem with bed bugs on the room they were in. 
2 weeks later, the resort confirmed the bed bug infestation.
The rest is history.  We got a phone call to K9- inspect her home that day. 
Fortunately, neither dogs alerted.  It was interesting to learn that the resort had requested that 2 independent canine inspections be performed within a week from each other.  They paid of course for all the charges, the travel costs, lodging and then some to their clients.

I could tell you more but it would have to be in dog language.   They really don't want humans to know...
 
 
To  minimize the risk of encountering bed bugs during your vacation, here are some
tips to follow:
 1. Prior to departure, check out bed bugs registry such as BedBugRegistry.com and HotelChatter.com to see if your hotel has been infested. 
2. Keep all luggage and carry-on bags off the floors and beds and out of the closets.  Put your luggage on the metal luggage racks in your room or better yet in the bathtub.  Hang clothes on the shower pole if possible, rather than hanging them in the closet.
 3. Before settling into your room, conduct a thorough inspection of hotel room. Look first in the most obvious areas such as the mattress and box spring for live specimen, blood spots, cast skins or brown spots.  Then check behind the headboard and the picture above the head board.  The nightstand and of course the armchairs.
 4. Another word of advice: Check out the rental car as well and ask the rental companies what their bed bug prevention
program entails.